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Update README.md
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andreaminio authored Nov 24, 2021
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Expand Up @@ -6,17 +6,14 @@ The aim of the tool is improving continuity of a given genome draft assembly up

![HaploSync Diagram](./manual/Workflows/Diagram.png)


HaploSync was developed to improve the quality of diploid genome assemblies. This tool:

* builds diploid pseudomolecule assemblies from draft sequences using
* a geteic map of features
* a reference genome as a guide
* enhances assembly contiguity,
* fills sequence gaps by comparing haplotypes independent of a reference,
* generates maps of the phased haplotypes,
* assesses the quality of assembled sequences
* edits sequences.
* Builds diploid pseudomolecule assemblies from draft sequences using:
* a genetic map
* a chromosome scaled guide genome of a closely related species
* Compares alternative haplotypes to identify and correct misassemblies independently from any reference
* Fills assembly gaps with un-placed sequences
* Resolves collapsed homozygous regions

## Resources
* [Go to manual](./manual/Readme.md)
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