diff --git a/src/FSharpPlus/Data/NonEmptyList.fs b/src/FSharpPlus/Data/NonEmptyList.fs
index d8f8834cd..86abb2865 100644
--- a/src/FSharpPlus/Data/NonEmptyList.fs
+++ b/src/FSharpPlus/Data/NonEmptyList.fs
@@ -494,6 +494,7 @@ module NonEmptyList =
     let init (count: int) (initializer: int -> 'T) : NonEmptyList<'T> = 
         Seq.init count initializer |> ofSeq
 
+#if !NET45
     /// <summary>Inserts an element at the specified index.</summary>
     /// <param name="index">The index at which to insert the element.</param>
     /// <param name="value">The value to insert.</param>
@@ -509,6 +510,7 @@ module NonEmptyList =
     /// <returns>The result list.</returns>
     let insertManyAt (index: int) (values: seq<'T>) (list: NonEmptyList<'T>) : NonEmptyList<'T> = 
         Seq.insertManyAt index values list |> ofSeq
+#endif
 
     /// <summary>Returns the element at the specified index.</summary>
     /// <param name="index">The index of the element to retrieve.</param>
@@ -673,6 +675,7 @@ module NonEmptyList =
     let inline range (start: 'T) stop = 
         create start (List.drop 1 [start..stop])
 
+#if !NET45
     /// <summary>Removes the element at the specified index.</summary>
     /// <param name="index">The index of the element to remove.</param>
     /// <param name="list">The input list.</param>
@@ -704,7 +707,8 @@ module NonEmptyList =
     /// <exception cref="System.ArgumentException">Thrown when removing the items results in an empty list.</exception>
     let removeManyAt (index: int) (count: int) (list: NonEmptyList<'T>) : NonEmptyList<'T> = 
         list |> Seq.removeManyAt index count |> ofSeq
-    
+#endif
+
     /// <summary>Creates a list that contains one repeated value.</summary>
     /// <param name="count">The number of elements.</param>
     /// <param name="value">The value to replicate.</param>
@@ -946,7 +950,8 @@ module NonEmptyList =
     /// <returns>A tuple containing the three lists.</returns>
     let unzip3 (list: NonEmptyList<'T1 * 'T2 * 'T3>) : NonEmptyList<'T1> * NonEmptyList<'T2> * NonEmptyList<'T3> = 
         list |> toList |> List.unzip3 |> fun (a, b, c) -> (ofList a, ofList b, ofList c)
-    
+
+#if !NET45
     /// <summary>Updates the element at the specified index.</summary>
     /// <param name="index">The index of the element to update.</param>
     /// <param name="value">The new value.</param>
@@ -954,7 +959,8 @@ module NonEmptyList =
     /// <returns>The result list.</returns>
     let updateAt (index: int) (value: 'T) (list: NonEmptyList<'T>) : NonEmptyList<'T> = 
         Seq.updateAt index value list |> ofSeq
-    
+#endif
+
     /// <summary>Returns a list that contains the elements of the list for which the given function returns <c>true</c>.</summary>
     /// <param name="predicate">A function to test each element of the list.</param>
     /// <param name="list">The input list.</param>
diff --git a/src/FSharpPlus/Data/NonEmptySeq.fs b/src/FSharpPlus/Data/NonEmptySeq.fs
index afea9d162..3aec54c68 100644
--- a/src/FSharpPlus/Data/NonEmptySeq.fs
+++ b/src/FSharpPlus/Data/NonEmptySeq.fs
@@ -477,7 +477,7 @@ module NonEmptySeq =
     /// <returns>The result sequence.</returns>
     let initInfinite initializer = 
         Seq.initInfinite initializer |> unsafeOfSeq
-
+#if !NET45
     /// <summary>Inserts an element at the specified index.</summary>
     /// <param name="index">The index at which to insert the element.</param>
     /// <param name="value">The value to insert.</param>
@@ -493,7 +493,7 @@ module NonEmptySeq =
     /// <returns>The result sequence.</returns>
     let insertManyAt (index: int) (values: seq<'T>) (source: NonEmptySeq<'T>) : NonEmptySeq<'T> = 
         Seq.insertManyAt index values source |> unsafeOfSeq
-
+#endif
     /// <summary>Returns the element at the specified index.</summary>
     /// <param name="index">The index of the element to retrieve.</param>
     /// <param name="source">The input sequence.</param>
@@ -696,6 +696,7 @@ module NonEmptySeq =
     let reduceBack (reduction: 'T -> 'T -> 'T)  (source: NonEmptySeq<'T>) = 
         Seq.reduceBack reduction source
 
+#if !NET45
     /// <summary>Removes the element at the specified index.</summary>
     /// <param name="index">The index of the element to remove.</param>
     /// <param name="source">The input sequence.</param>
@@ -727,7 +728,8 @@ module NonEmptySeq =
     /// <exception cref="System.ArgumentException">Thrown when removing the items results in an empty sequence.</exception>
     let removeManyAt (index: int) (count: int) (source: NonEmptySeq<'T>) : NonEmptySeq<'T> = 
         Seq.removeManyAt index count source |> ofSeq
-    
+#endif
+
     /// <summary>Creates a sequence that contains one repeated value.</summary>
     /// <param name="count">The number of elements.</param>
     /// <param name="value">The value to replicate.</param>
@@ -1040,7 +1042,8 @@ module NonEmptySeq =
     /// <returns>A tuple containing the three sequences.</returns>
     let unzip3 (source: NonEmptySeq<'T1 * 'T2 * 'T3>) : NonEmptySeq<'T1> * NonEmptySeq<'T2> * NonEmptySeq<'T3> = 
         source |> Seq.toList |> List.unzip3 |> fun (a, b, c) -> (unsafeOfSeq a, unsafeOfSeq b, unsafeOfSeq c)
-    
+
+#if !NET45
     /// <summary>Updates the element at the specified index.</summary>
     /// <param name="index">The index of the element to update.</param>
     /// <param name="value">The new value.</param>
@@ -1048,7 +1051,8 @@ module NonEmptySeq =
     /// <returns>The result sequence.</returns>
     let updateAt (index: int) (value: 'T) (source: NonEmptySeq<'T>) : NonEmptySeq<'T> = 
         Seq.updateAt index value source |> unsafeOfSeq
-    
+#endif
+
     /// <summary>Returns a sequence that contains the elements of the sequence for which the given function returns <c>true</c>.</summary>
     /// <param name="predicate">A function to test each element of the sequence.</param>
     /// <param name="source">The input sequence.</param>