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DESCRIPTION
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Package: oncomix
Title: Identifying Genes Overexpressed in Subsets of Tumors from Tumor-Normal mRNA
Expression Data
Version: 0.99.3
Author: Daniel Pique, John Greally, Jessica Mar
Maintainer: Daniel Pique <daniel.pique@med.einstein.yu.edu>
Description: This package helps identify mRNAs that are overexpressed in subsets
of tumors relative to normal tissue. Ideal inputs would be paired tumor-normal
data from the same tissue from many patients (>15 pairs). This unsupervised
approach relies on the observation that oncogenes are characteristically
overexpressed in only a subset of tumors in the population, and may help
identify oncogene candidates purely based on differences in mRNA expression
between previously unknown subtypes.
Depends:
R (>= 3.4.0)
License: GPL-3
Encoding: UTF-8
LazyData: true
RoxygenNote: 6.0.1
Suggests:
knitr,
rmarkdown,
testthat,
RMySQL
Imports:
ggplot2,
ggrepel,
RColorBrewer,
mclust,
stats,
SummarizedExperiment
VignetteBuilder: knitr
biocViews: GeneExpression, Sequencing