This repository contains the two R scripts used in the paper titled Treg fitness as a biomarker for disease activity in Juvenile Idiopathic Arthritis by M. H. Attrill et al.

• The Pesenacker_Tregsig_nanostring_normalisation.R script implements the normalisation and transformation of the nanostring data.
• The Pesenacker_Tregsig_biomarker_discovery_pipeline.R script implements the model used for biomarker discovery.

Note

Users should note that the data used in the paper can be downloaded from [?]. To run the scripts on the data, users must save the data in the same folder as the scripts.