Add table PACK_CONTENT

[cgreich]

This table already exists, we just never put it into the CDM documentation and haven't included it in the vocabulary zip file. This would be the chapter:

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Table Description

The PACK_CONTENT table contains structured content of drug Packs. Packs are fixed combination of Drugs (Clinical Drugs, Branded Drug, Quant Clin Drug, Quant Branded Drug, Marketed Product without box size information). For example, contraceptives contain a certain amount of progesteron drug and estrogen preparations, sufficient for a month. This table is supplemental information to support standardized analysis of drug utilization.

User Guide

NA

ETL Conventions

The content of the table is part of the OHDSI Standardized Vocabularies and should be loaded with each release.

CDM Field	User Guide	ETL Conventions	Datatype	Required	Primary Key	Foreign Key	FK Table	FK Domain
pack_concept_id	The Concept representing the Pack.	N/A	integer	Yes	No	Yes	CONCEPT
drug_concept_id	The Concept representing the individual drug component inside the Pack.	N/A	integer	Yes	No	Yes	CONCEPT
amount	The number of the above Drug  components in the Pack.	N/A	integer	No	No	No
box_size	The number of Packs in a Drug Box.	N/A	integer	No	No	No

[ekorchmar]

To iterate on importance of this: currently, any and all HADES tools (e.g. those deriving DOSE_ERA) requiring drug dosage information ever only query the DRUG_STRENGTH table. At the same time, when source drug concepts are standardized to OMOP, the PACK_CONTENT table is populated with non-redundant data. That means that in current definition of OMOP CDM, actual dosage information for "pack-shaped" concepts is irretrievable.

https://github.com/search?q=repo%3AOHDSI%2FVocabulary-v5.0%20%22PACK_CONTENT%22&type=code

Although use of DOSE_ERA as well as dosage information in general in OMOP is rare, this needs to be fixed.

[clairblacketer]

Potential concerns over drug_era calculations downstream. Based on @ekorchmar's comment above we should create a child issue detailing any updates to dose calculations that need to be implemented with the addition of the pack_content table